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NovoSeven® RT (coagulation Factor VIIa, recombinant) logo
Important Safety Information | Patient Site
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    • Why NovoSeven® RT?
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NovoSeven® RT (coagulation Factor VIIa, recombinant) logo

Indicated for treatment of bleeding episodes and perioperative management in adults and children with hemophilia A or B with inhibitors, congenital factor VII (FVII) deficiency, Glanzmann’s thrombasthenia with refractoriness to platelet transfusions and in adults with acquired hemophilia.

Prescribing Information
Important Safety Information | Patient Site
Support for your patients

Novo Nordisk believes providing financial support through NovoSecure™, a network that helps your eligible patients access co-pay savings, product assistance, and more.

Support for your patients

Novo Nordisk believes in providing financial support through NovoCare®, a network that helps your eligible patients access co-pay savings, product assistance, and more.


Parent and child smiling

NovoSecure™ is designed for your patients

By creating a NovoSecure™ account, your patients can access:

  • Product support programs that help with treatment costs
  • Representatives who speak Spanish to better serve more patients

A Novo Nordisk Representative can help you connect patients with these resources. Or, you can send your patients to MyNovoSecure.com 

NovoCare® is designed for your patients

By creating a NovoCare® account, your patients can access:

  • Product support programs that help with treatment costs
  • Representatives who speak Spanish to better serve more patients

A Novo Nordisk Representative can help you connect patients with these resources. Or, you can send your patients to NovoCare.com 


Insurance coordination

Help with benefits verification

We can help you verify your patient’s benefits with QuickCheck™. Submit the form to receive a Summary of Benefits, generally within 4 hours,a from 9:00 am to 4:00 pm Eastern time.

  1. Download the QuickCheck™ Form
  2. Fax it to NovoCare® at 1-866-488-6576
  3. Or email to: novocarespecialist@novocare.com

aQuickCheck™ benefits verification can be completed within 4 hours only if all required information has been submitted.

QuickCheck™ Benefits Verification Form
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QuickCheck™ Benefits Verification Form
The QuickCheck™ form will allow NovoCare® to verify your patients’ benefits and provide additional insurance-related information.
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Other support options for your patients

Eligible patients may be able to save on prescription costsb or qualify for our product assistance program.c Use the tools below to get started and see how we can help patients using NovoSeven® RT.

Co-pay Assistance
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Co-pay Assistance
See if your patients are eligible to receive a hemophilia savings card.
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Product Assistance Program
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Product Assistance Program
Download the form to see if your patients qualify for our Product Assistance Program.
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Interim Product Program

Interim Product Program logo

This limited program provides therapy to qualifying patientsd during a coverage gap. Contact a NovoCare® Specialist by calling 1-844-668-6732.

Free Trial Prescription

NovoSeven® RT (coagulation Factor VIIa, recombinant) box and contents

Novo Nordisk is here to help your hemophilia A patients who want to make the switch to NovoSeven® RT. Learn about our trial prescriptiond and product support programs.

To learn more about our trial prescription program, please call 1-844-668-6732 to speak with a NovoCare® Specialist.

bNovo Nordisk Hemophilia and Rare Bleeding Disorders Copay/Coinsurance Terms and Conditions: 

Enrolled patients are eligible for up to $12,000 in co-pay/coinsurance assistance per calendar year for each NNI hemophilia or rare bleeding disorder product. Assistance is retroactive to 60 days. Patients must be commercially insured and may not be participating in any government, state, or federally funded medical or prescription benefit programs, including Medicare, Medicaid, Medigap, VA, DOD, and TRICARE, including patients who participate in a managed Medicaid program or have Medicaid as secondary insurance. Uninsured, cash-paying patients are not eligible to participate. Patients are eligible to receive co-pay/coinsurance assistance on an annual basis (12 months). Offer good only in the USA, Puerto Rico, Guam, Saipan, and Virgin Islands with participating pharmacies and cannot be redeemed at government-subsidized clinics. Void where taxed, restricted, or prohibited by law. The Savings Card is no longer valid for residents of Massachusetts. Patient is responsible for complying with any insurance carrier co-payment disclosure requirements, including disclosing any savings received from this program. Re-confirmation of information may be requested periodically to ensure accuracy of data and compliance with terms. This is not an insurance program. Novo Nordisk reserves the right to rescind, revoke, or amend this offer without notice at any time. Non-medication expenses, such as ancillary supplies or administration-related costs, are not eligible. Must have a current prescription for an FDA-approved indication.

cThe Novo Nordisk Patient Assistance Program (PAP) is administered by NovoCare® To qualify for the PAP, patients must demonstrate financial need and must have attempted to find alternative reimbursement. Several factors are considered in evaluating financial need, including cost of living, size of household, and burden of total medical expenses. If the applicant qualifies under the PAP guidelines, a limited supply of the requested medication(s) will be shipped to the patient. Patients who qualify for PAP may be eligible to receive the prescribed Novo Nordisk product, for up to 1 year from the approval date. Product limits vary.

dPatients who have been prescribed a Novo Nordisk hemophilia and rare bleeding disorder product for an FDA-approved indication, and who have commercial insurance, may be eligible to receive a limited supply of free product. Patients who participate in any government, state, or federally funded medical or prescription benefit programs, including Medicare, Medicaid, Medigap, VA, DOD, and TRICARE, including patients who participate in a managed Medicaid program or have Medicaid as secondary insurance, are not eligible to receive product support. Product is provided at no cost to the patient or the HCP, is not contingent on any product purchase, and the patient and HCP must not: (1) bill any third party for the free product, or (2) resell the free product.

Looking for other NovoSeven® RT resources?

NovoSeven® RT Mechanism of Action

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Patient education materials

Help patients learn about bleeding disorders.

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Selected Important Safety Information for NovoSeven® RT

WARNING: THROMBOSIS

  • Serious arterial and venous thrombotic events following administration of NovoSeven® RT have been reported
  • Discuss the risks and explain the signs and symptoms of thrombotic and thromboembolic events to patients who will receive NovoSeven® RT
  • Monitor patients for signs or symptoms of activation of the coagulation system and for thrombosis

Warnings and Precautions

  • Serious arterial and venous thrombotic events have been reported in clinical trials and postmarketing surveillance
  • Patients with congenital hemophilia receiving concomitant treatment with aPCCs (activated prothrombin complex concentrates), older patients particularly with acquired hemophilia and receiving other hemostatic agents, and patients with a history of cardiac and vascular disease may have an increased risk of developing thrombotic events

Indications and Usage

NovoSeven® RT (coagulation Factor VIIa, recombinant) is a coagulation factor indicated for:

  • Treatment of bleeding episodes and perioperative management in adults and children with hemophilia A or B with inhibitors, congenital Factor VII (FVII) deficiency, and Glanzmann’s thrombasthenia with refractoriness to platelet transfusions, with or without antibodies to platelets
  • Treatment of bleeding episodes and perioperative management in adults with acquired hemophilia

Important Safety Information

WARNING: THROMBOSIS

  • Serious arterial and venous thrombotic events following administration of NovoSeven® RT have been reported
  • Discuss the risks and explain the signs and symptoms of thrombotic and thromboembolic events to patients who will receive NovoSeven® RT
  • Monitor patients for signs or symptoms of activation of the coagulation system and for thrombosis

Warnings and Precautions

  • Serious arterial and venous thrombotic events have been reported in clinical trials and postmarketing surveillance
  • Patients with congenital hemophilia receiving concomitant treatment with aPCCs (activated prothrombin complex concentrates), older patients particularly with acquired hemophilia and receiving other hemostatic agents, and patients with a history of cardiac and vascular disease may have an increased risk of developing thrombotic events
  • Hypersensitivity reactions, including anaphylaxis, can occur with NovoSeven® RT. Patients with a known hypersensitivity to mouse, hamster, or bovine proteins may be at a higher risk of hypersensitivity reactions. Discontinue infusion and administer appropriate treatment when hypersensitivity reactions occur
  • Factor VII deficient patients should be monitored for prothrombin time (PT) and factor VII coagulant activity (FVII:C). If FVII:C fails to reach the expected level, or PT is not corrected, or bleeding is not controlled after treatment with the recommended doses, antibody formation may be suspected and analysis for antibodies should be performed
  • Laboratory coagulation parameters (PT/INR, aPTT, FVII:C) have shown no direct correlation to achieving hemostasis

Adverse Reactions

  • The most common and serious adverse reactions in clinical trials are thrombotic events. Thrombotic adverse reactions following the administration of NovoSeven® RT in clinical trials occurred in 4% of patients with acquired hemophilia and 0.2% of bleeding episodes in patients with congenital hemophilia

Drug Interactions

  • Thrombosis may occur if NovoSeven® RT is administered concomitantly with Coagulation Factor XIII

Please click here for NovoSeven® RT Prescribing Information, including Boxed Warning.

Rare Bleeding Disorders
Other Therapy Areas
Explore diabetes
Explore obesity
Explore rare bleeding disorders
Explore growth-related disorders
Explore hormone replacement therapy
  • Rare Bleeding Disorders Home
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