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rare renal disorders

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Primary hyperoxaluria type 1 (PH1) is a rare genetic disorder that can lead to recurrent kidney stones and progressive kidney damage.1,2

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References:

  1. Lai C, Pursell N, Gierut J, et al. Specific inhibition of hepatic lactate dehydrogenase reduces oxalate production in mouse models of primary hyperoxaluria. Mol Ther. 2018;26(8):1983-1995. doi:10.1016/
 j.ymthe.2018.05.016
  2. Soliman NA, Nabhan MM, Abdelrahman SM, et al. Clinical spectrum of primary hyperoxaluria type 1: experience of a tertiary center. Nephrol Ther. 2017;13(3):176-182. doi:10.1016/j.nephro.2016.08.002
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