ASCVD=atherosclerotic cardiovascular disease; MI=myocardial infarction; T2D= type 2 diabetes; CI=confidence interval.
aThe ACC defines ASCVD as: a history of an acute coronary syndrome or MI, stable or unstable angina, coronary heart disease with or without revascularization, other arterial revascularization, stroke, or peripheral artery disease assumed to be atherosclerotic in origin.6
bResults from a large retrospective cohort study in patients newly diagnosed with T2D between 2003 and 2014 (n=135,199). Using data from a large U.S. integrated health care system, this study estimated the prevalence and incidence of 13 microvascular and macrovascular complications, including chronic kidney disease, CVD, and all-cause mortality over a 15-year period. Multivariate Cox proportional-hazards models were used to study factors associated with complications. Incidence is defined as incidence rate per 1000 person-years. Combined incidence of ASCVD includes individual incident rates of MI, unstable and stable angina, stroke, and peripheral vascular disease. The incidence rate per 1000 person-years for composite CVD, defined as MI, unstable angina, and stroke, was 11.9, 95% CI (11.7-12.2).5