NOVOMEDLINK™

Efficacy of NovoLog®

Improved control for patients not at goal

For patients who are currently not reaching their goals with other treatments, NovoLog® has a lot to offer.

NovoLog® provides significantly better mean postprandial plasma glucose (PPG) levels — up to 30 mg/dL lower — after three meals compared with regular human insulin26,27

6–month, randomized, open-label, parallel-group study enrolling 882 patients who had had type 1 diabetes for at least 18 months. There was a six–month extension of this trial.26





NovoLog® reduces nocturnal hypoglycemic episodes27,28

Sixteen-week, double-blind, randomized, crossover trial enrolling 155 patients who had had type 1 diabetes for at least 2 years. A 72% reduction in nocturnal hypoglycemia was documented.28

  1. NovoLog® (insulin aspart [rDNA origin] injection) Indications and Usage

    NovoLog® is an insulin analog indicated to improve glycemic control in adults and children with diabetes mellitus.

    NovoLog® Important Safety Information

    NovoLog® is contraindicated during episodes of hypoglycemia and in patients hypersensitive to NovoLog® or one of its excipients.

    NovoLog® has a more rapid onset and shorter duration of action than regular human insulin. An injection of NovoLog® should be immediately followed by a meal within 5 to 10 minutes. Because of the short duration of action of NovoLog®, a longer-acting insulin also should be used in patients with type 1 diabetes and may be needed in patients with type 2 diabetes. When used in an external subcutaneous insulin infusion pump, NovoLog® should not be mixed with any other insulin or diluent. Hypoglycemia is the most common adverse effect of all insulin therapies, including NovoLog®. The timing of hypoglycemia usually reflects the time-action profile of the administered insulins.

    Any change of insulin dose should be made cautiously and only under medical supervision. Glucose monitoring is recommended for all patients with diabetes and is particularly important for patients using external pump infusion therapy. As with all insulin preparations, the time course of action of NovoLog® may vary in different individuals or at different times in the same individual and is dependent on many conditions, including injection site, local blood supply, temperature, and level of physical activity.

    Severe, life-threatening generalized allergy, including anaphylactic reaction, may occur with any insulin product, including NovoLog®. Adverse reactions observed with NovoLog® include hypoglycemia, allergic reactions, local injection site reactions, lipodystrophy, rash, and pruritus. Insulin, particularly when given intravenously or in settings of poor glycemic control, may cause hypokalemia. Like all insulins, NovoLog® requirements may be reduced in patients with renal impairment or hepatic impairment.

    Please see Prescribing Information.